Cloning and expression studies of cDNA for a novelXenopus cadherin (XmN-cadherin), expressed maternally and later neural-specifically in embryogenesis

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Cloning and expression studies of cDNA for a novelXenopus cadherin (XmN-cadherin), expressed maternally and later neural-specifically in embryogenesis

From a Xenopus tailbud cDNA library, we obtained the cDNA for a novel cadherin which was named as XmN-cadherin (Xenopus maternally expressed neural cadherin). The cDNA consisted of 3690 bp and encoded 922 amino acid residues. XmN-cadherin preserved five extracellular cadherin motifs, a single transmembrane domain, and a cytoplasmic domain, and was closely related by its sequence to R- and N-cad...

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Cloning and expression of cDNA encoding a neural calcium-dependent cell adhesion molecule: its identity in the cadherin gene family

The neural cadherin (N-cadherin) is a Ca2+-dependent cell-cell adhesion molecule detected in neural tissues as well as in non-neural tissues. We report here the nucleotide sequence of the chicken N-cadherin cDNA and the deduced amino acid sequence. The sequence data suggest that N-cadherin has one transmembrane domain which divides the molecule into an extracellular and a cytoplasmic domain; th...

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ژورنال

عنوان ژورنال: Mechanisms of Development

سال: 1996

ISSN: 0925-4773

DOI: 10.1016/0925-4773(95)00469-6